GMP Standard Spray Drying for Pharmaceutical and Traditional Chinese Medicine Extracts
Overviews
QZR series spray drying equipment is fully enclosed. All parts are made of 304 or 316L stainless steel, equipped with a three-stage purification device. The filtered air reaches the 100,000 level requirement. The cylinder is equipped with a cold wall device to reduce wall temperature and dry. The tower is equipped with an air-brushing tower sweeping device, and the Chinese medicine extract powder dried by the machine will not cause coking and metamorphism, greatly increase the powder collection rate, and will not cause the phenomenon of mixed drugs and sticking walls. .
Chinese medicine extract high-speed centrifugal spray device is the application of centrifugal spray drying technology to specific materials. It also uses high-speed centrifugal atomizers to disperse the materials into a mist and fully contact with hot air. Drying device. The difference between traditional Chinese medicine extract high-speed centrifugal spraying device and ordinary high-speed centrifugal spray-drying device is that it solves the junior high-efficiency three-stage filtration of air, and the instantaneous and rapid solidification of the dried materials. Repeated heating prevents the effective components of the material from being heated and volatilized and decomposed, and solves key technologies such as tower pipe cleaning.
For more efficient cleaning of traditional Chinese medicine extract equipment, a CIP full-automatic cleaning system can be selected. Automatic retractable cleaning heads are installed in various parts of the drying equipment to achieve online cleaning without dismantling the pipelines. The cleaning water can also be recycled for more energy-saving More efficient and environmentally friendly. The control system is a DCS intelligent control system, which can realize one-click cleaning. The CIP automatic cleaning system ensures that the spray drying tower system has no hygienic dead corners, and its cleaning results meet the new GMP standard and can be verified.
Dry materials
| Dry materials | Chinese medicine extract |
| Inlet temperature | 160-180℃ |
| Outlet temperature | 80-90℃ |
| Output | 5KG—300KG |
| Heating method | 6kg/cm2 saturated steam + electric heater |
| Residual moisture content of the product | 4-7％ |
| Spray method | High-speed centrifugal co-current drying |
| Product collection method | first-level cyclone separator, second-level wet dust collector |
Equipment requirements
1.All the materials in contact with the equipment are made of stainless steel 304 plate, and the inner wall of the drying tower is mirror polished.
2.The atomizer is equipped with a secondary air inlet.
3.The equipment is equipped with an air cleaning system.
4.This equipment meets GMP requirements.
5.The main channel adopts 304 stainless steel quick connection.
6.The equipment is equipped with cone air-cooled jacket and air hammer vibration system.
7.The equipment is equipped with dry powder dehumidification air cooling system.
QZR series spray drying equipment is fully enclosed. All parts are made of 304 or 316L stainless steel, equipped with a three-stage purification device. The filtered air reaches the 100,000 level requirement. The cylinder is equipped with a cold wall device to reduce wall temperature and dry. The tower is equipped with an air-brushing tower sweeping device, and the Chinese medicine extract powder dried by the machine will not cause coking and metamorphism, greatly increase the powder collection rate, and will not cause the phenomenon of mixed drugs and sticking walls.
Chinese medicine extract high-speed centrifugal spray device is the application of centrifugal spray drying technology to specific materials. It also uses high-speed centrifugal atomizers to disperse the materials into a mist and fully contact with hot air. Drying device. The difference between traditional Chinese medicine extract high-speed centrifugal spraying device and ordinary high-speed centrifugal spray-drying device is that it solves the junior high-efficiency three-stage filtration of air, and the instantaneous and rapid solidification of the dried materials. Repeated heating prevents the effective components of the material from being heated and volatilized and decomposed, and solves key technologies such as tower pipe cleaning.
For more efficient cleaning of traditional Chinese medicine extract equipment, a CIP full-automatic cleaning system can be selected. Automatic retractable cleaning heads are installed in various parts of the drying equipment to achieve online cleaning without dismantling the pipelines. The cleaning water can also be recycled for more energy-saving More efficient and environmentally friendly. The control system is a DCS intelligent control system, which can realize one-click cleaning. The CIP automatic cleaning system ensures that the spray drying tower system has no hygienic dead corners, and its cleaning results meet the new GMP standard and can be verified.
| 1 | Dry materials | Chinese medicine extract |
| 2 | Inlet temperature | 160-180℃ |
| 3 | Outlet temperature | 80-90℃ |
| 4 | Output | 5KG—300KG |
| 5 | Heating method | 6kg/cm2saturated steam + electric heater |
| 6 | Residual moisture content of the product | 4-7％ |
| 7 | Spray method | High-speed centrifugal co-current drying |
| 8 | Product collection method | first-level cyclone separator, second-level wet dust collector |
